Adhering to the principle of “Improve the team effectiveness by scientific and technological innovation, shape the brand competitiveness by core technology, enhance the enterprise vitality by product quality”, R&D center focus on the synthesis of small molecule drugs, develop a series of core technology for bromination, enzyme/metal catalysis, nitration, hydrogenation reaction, etc., build the green intelligent R&D platform, and complete the synthetic route design, target product synthesis, molecular structure confirmation, process route optimization, pilot plant test and industrialization study efficiently. In the past three years, the process development of more than 300 small molecule drugs has been completed.
Chiral synthesis
Catalytic technologies using organo-transition metal chemistry
Grignard reactions
Oxidations (hydrogen peroxide, sodium hypochlorite, Swern type etc.)
High and low pressure preparation column separation
Ion exchange chromatography
Asymmetric amino acids transformations by diazotation
Low and High temperature reactions (-40℃~250℃)
Chiral synthesis
Catalytic technologies using organo-transition metal chemistry
Grignard reactions
Oxidations (hydrogen peroxide, sodium hypochlorite, Swern type etc.)
High and low pressure preparation column separation
Ion exchange chromatography
Asymmetric amino acids transformations by diazotation
Low and High temperature reactions (-40℃~250℃)
Metal-organic chemistry
Synthesis of chiral compounds
Mild and catalytic C-C bond forming reactions (including Heck reaction and Suzuki-Myaura)
Enzyme catalytical Chemistry
Heterocyclic chemistry
Metal-organic chemistry
Synthesis of chiral compounds
Mild and catalytic C-C bond forming reactions (including Heck reaction and Suzuki-Myaura)
High and low pressure preparation column separation
Ion exchange chromatography
Asymmetric amino acids transformations by diazotation
Low and High temperature reactions (-40℃~250℃)
Copyright Nanjing Dorra Pharmaceutical Technology Co.,Ltd. @ 2018 China All Rights Reserved 苏ICP备12056923号-1