核心技术

Core Technology

Adhering to the principle of “Improve the team effectiveness by scientific and technological innovation, shape the brand competitiveness by core technology, enhance the enterprise vitality by product quality”, R&D center focus on the synthesis of small molecule drugs, develop a series of core technology for bromination, enzyme/metal catalysis, nitration, hydrogenation reaction, etc., build the green intelligent R&D platform, and complete the synthetic route design, target product synthesis, molecular structure confirmation, process route optimization, pilot plant test and industrialization study efficiently. In the past three years, the process development of more than 300 small molecule drugs has been completed.

Key Technologies

Chiral synthesis

Catalytic technologies using organo-transition metal chemistry

Grignard reactions

Oxidations (hydrogen peroxide, sodium hypochlorite, Swern type etc.)

High and low pressure preparation column separation

Ion exchange chromatography

Asymmetric amino acids transformations by diazotation

Low and High temperature reactions (-40℃~250℃)

Chiral synthesis

Catalytic technologies using organo-transition metal chemistry

Grignard reactions

Oxidations (hydrogen peroxide, sodium hypochlorite, Swern type etc.)

High and low pressure preparation column separation

Ion exchange chromatography

Asymmetric amino acids transformations by diazotation

Low and High temperature reactions (-40℃~250℃)

Chemical Expertise

Metal-organic chemistry

Synthesis of chiral compounds

Mild and catalytic C-C bond forming reactions (including Heck reaction and Suzuki-Myaura)

Enzyme catalytical Chemistry

Heterocyclic chemistry

Metal-organic chemistry

Synthesis of chiral compounds

Mild and catalytic C-C bond forming reactions (including Heck reaction and Suzuki-Myaura)

High and low pressure preparation column separation

Ion exchange chromatography

Asymmetric amino acids transformations by diazotation

Low and High temperature reactions (-40℃~250℃)

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